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Give It A Clear Advantage Over Epogen US Makers But Trumps
10-13-2018, 12:14 AM
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Two clinical studies and an editorial published in the New England Journal of Medicine last November addressed safety concerns about the use of erythropoiesis stimulating agents in the treatment of anemia of chronic renal failure.

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Hemodialysis equipment and disposables used for treatment can fail, causing treatment interruptions and delays and possible patient harm.

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In fact, up until 1994 there have been only 67 well documented cases in medical literature.

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To put it differently generics have identical active ingredients and their pharmacological effects are the same, as those of their brand-name equivalents.

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Epoetin alfa may also be used for purposes not listed in this medication guide.

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In just five to seven minutes, a patient receiving hemodialysis treatment can lose 40% of his or her blood volume from a venous needle dislodgment, resulting in a class IV hemorrhage, the most serious of hemorrhage classifications indicating the need for aggressive treatment to prevent death.

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We also laid the foundation for future success with our new product launches, as well as further expansion into new countries, while transforming our customer-facing model and delivering significant cost savings, which we reinvested in the launches.

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The purple book will contain lists of all licensed biosimilar and interchangeable biological products and will act as a reference once approvals are made in the US.

As opposed to normal conditions, with low basal erythropoietin concentrations and slower rates of red cell production, injection of pharmacologic doses of ESAs probably results in nonphysiologic rapid rates of red cell production.

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Three double-blind, placebo-controlled studies, including 244 patients with CKD on dialysis, were used to identify the adverse reactions to Epogen.

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